Invincibility and shields will not trigger a sacrifice (including Holy Mantle).After the Afterbirth patch, you now unlock the Lost by dying in a sacrifice room while carrying the Missing Poster.Dying in a sacrifice room while holding Missing Poster will unlock The Lost.The Dark Room teleport still happens on any floor even if you haven't unlocked it yet.The sacrifice room door stays open during the Angel fights, meaning they can be skipped to proceed to the next level of sacrificing without killing them.A payout is randomly chosen from each of the possible ones for that sacrifice.The 'You feel blessed!' buffs can even allow an Angel Room to spawn after taking a Devil Deal.Teleport directly to the Dark Room floor (50% chance)Ī big thank you to Zamie who did the research and added the above stats to the Sacrifice Room Wiki page.Gabriel Angel mini-boss spawns (100% chance).30 Coins (50% chance) - Cannot be Nickels or Dimes.Uriel Angel mini-boss spawns (100% chance).Teleport to the Devil or Angel Room (33% chance).- This increased chance has a value of 50% * (Devil Room chance).'You feel blessed!' buff (66% chance) - Increased chance to see an Angel Room in favour of a Devil Room on the current floor.3 Coins (33% chance) - Cannot be Nickels or Dimes.- This increased chance has a value of 15% * (Devil Room chance).1 Coin (50% chance) - Cannot be Nickels or Dimes.The below table details each level of payout and the reward for reaching each tier: Number of Sacrifices
The Sacrifice Room now has various different levels of rewards, depending on the amount of times used on the same floor. Historically, Sacrifice Rooms have always been pretty darn useless in The Binding of Isaac, but lucky owners of the Afterbirth DLC will find they've had a huge revamp, significantly increasing the quality of rewards you can find.
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